Metabolism, Glands, Bones, Blood, Cells, Digestion, Nerves....

In its 'obesity' overview -"the term describes a person who is very overweight, with a lot of body fat", the NHS tells us;
"Risks of obesity" are,

Type 2 diabetes, coronary heart disease, some types of cancer , such as breast and bowel cancer and stroke....depression.

That should be post menopause breast cancer, but what's a small AM/PM detail?
"Other obesity-related problems" - "Obesity can cause a number of further problems, including difficulties with daily activities and serious health conditions."

breathlessness, increased sweating, snoring, difficulty doing physical activity, often feeling very tired, joint and back pain, low confidence and self-esteem, feeling isolated.....depression.

It continues, "Being obese can also increase your risk of developing many potential serious health conditions, including:

type 2 diabetes, high blood pressure, high cholesterol, atherosclerosis (where fatty deposits narrow your arteries), which can lead to coronary heart disease and stroke, asthma, metabolic syndrome, a combination of diabetes, high blood pressure and obesity, several types of cancer....bowel...breast...womb, gastroesophageal reflux disease (GORD), where stomach acid leaks out of the stomach into the gullet, gallstones, reduced fertility, osteoarthritis, a condition involving pain and stiffness in your joints, sleep apnoea, a condition that causes interrupted breathing during sleep, which can lead to daytime sleepiness with an increased risk of road traffic accidents, as well as a greater risk of diabetes, high blood pressure and heart disease, liver and kidney disease, pregnancy complications, such as gestational diabetes

Got that? Metabolism, glands, blood, cellular reproduction, digestion, nervous system. Better watch out! Being human is a serious condition, it can cause all sorts of problems, difficulties and diseases.